MATERIAL SAFETY DATA SHEET
1. CHEMICAL PRODUCT AND COMPANY INDENTIFICATION
Product: FORMAzol
Cat. No: FO 121
Molecular Research Center
5645 Montgomery
Rd.
Cincinnati, Ohio 45212
USA 1-888-841-0900
Product Name: FORMAzol
Chemical Name: A formulation
Molecular Weight: 45.04
Synonyms: Carbamaldehyde, Methanamide
NFPA RATINGS: (Scale 0-4) Health=2 Fire=1 Reactivity=0 PPE=D*
HMIS RATINGS: (Scale
0-4) Health=2 Fire=1 Reactivity=0
Use chemical fume hood
for adequate ventilation.
CHEMTREC EMERGENCY
NUMBER 1-800-262-8200
2. COMPOSITION
AND INFORMATION ON INGREDIENTS
Component CAS No. EINECS/ELINCS Percent
Formamide 75-12-7 200-842-0 Proprietary
Information
3. HEALTH
HAZARD INFORMATION
EFFECTS OF OVEREXPOSURE: May cause respiratory and digestive tract
irritation. May cause eye and skin
irritation. May cause reproductive and
fetal effects. Target organs: Central
nervous system,liver, eyes, reproductive system, skin, mucous membranes.
ROUTES OF ENTRY: Inhalation Yes
Skin Yes
Ingestion Yes
ACUTE EFFECTS
EYE EXPOSURE: May cause eye irritation.
SKIN EXPOSURE: May cause skin irritation and mucus membrane
irritation. Symptoms include redness,
itching and pain. Harmful if exposed through skin. Not expected to cause an
allergic reaction.
INGESTION: May cause irritation of the digestive tract. Affects the central nervous system. May cause headache, dizziness, nausea,
vomiting, abdominal pain, and unconsciousness. May affect reproductive system.
INHALATION: May cause respiratory tract irritation. Inhalation of high concentrations may cause
central nervous system effects including headache, dizziness, unconsciousness
and coma.
CHRONIC EFFECTS
Prolonged and repeated
exposure may cause birth defects including congenital malformation in the
fetus. Chronic exposure may cause liver
damage. There is a danger of cumulative
effects.
4. FIRST AID
EYE CONTACT: Immediately flush eyes with copious amounts of
water for 15 minutes while lifting upper and lower lids. Get medical attention.
SKIN CONTACT: Remove contaminated
clothing. Flush skin with soap and
water for 15 minutes. Get medical
treatment if irritation develops and persists.
INHALATION: Remove to fresh air. Get medical aid immediately.
If not breathing, give artificial respiration.
If breathing is difficult, give oxygen.
INGESTION: If victim is conscious, wash mouth out with
water. If swallowed, do not induce
vomiting unless directed to do so by medical personnel. Get medical attention immediately.
5. FIRE AND
EXPLOSION HAZARD DATA
Emits toxic fumes
under fire conditions such as carbon monoxide, and ammonia. Wear self-contained breathing apparatus and
MSHA/NIOSH approved protective gear.
Flash point: 309 F, 154 C Moderate fie hazard when heated.
Explosion limits: lower 2.70 (% by volume)
upper
19.00
Autoignition
temperature: 932 F
EXTINGUISHING
MEDIA: Water spray, water foam,
carbon dioxide, dry chemicals. Wear self-contained breathing apparatus or
approved respirator.
6. ACCIDENTAL
RELEASE MEASURES
PERSONAL PROTECTIVE
EQUIPMENT: Use gloves, boots,
safety glasses, other impervious clothing to avoid skin contact.
SPILLS OR LEAKS: Ventilate area of leak or spill. Wear self-contained breathing apparatus and
MSHA/NIOSH approved protective gear. Absorb spill with earth, sand, vermiculite
or other non-combustible material and place in sealed containers. Do not use combustible materials such as saw
dust and do not flush into sewer.
7. HANDLING
AND STORAGE
Use with
adequate ventilation and wash hands thoroughly after handling. Store the reagent in a cool, dry and
well-ventilated area. Refrigeration may
be appropriate for long-term storage or sporadic use. Keep container tightly closed to avoid exposure. Do not store in direct sunlight.
8. EXPOSURE
CONTROLS, PERSONAL PROTECTION
PERSONAL
PROTECTIVE EQUIPMENT:
Wear appropriate eye protection, gloves and lab coat for routine
operations. Do not eat or drink in area
where reagent is used. Avoid contact
with skin and eyes. Do not breathe
vapor. Laboratory should be equipped
with an eye wash station
9. PHYSICAL
AND CHEMICAL PROPERTIES
Description: Clear, colorless
liquid with weak ammonia-like odor
Chemical
formula: CH3NO
Molecular
weight: 45.04
Melting
point: 2-4 C
Boiling
point: 210 C
Density
1.132 g/cm3
Vapor
pressure: .06 mm Hg @
25 C
Solubility: misc. with water
Sol.
in ethanol, acetone
pH value: 4-5 (20% in water,
20 C)
10.
STABILITY AND REACTIVITY
STABILITY:
Stable at room
temperature and pressure. Avoid ignition sources, excess heat. Avoid light, moisture and temperatures above
180 C.
INCOMPATIBILITIES:
Aluminum, acids,
bases, strong oxidizing agents, calcium nitrate, iodine, pyridine and sulfur
trioxide. Copper, brass, lead and
rubber are attacked by formamide.
HAZARDOUS
DECOMPOSITION PRODUCTS:
Nitrogen oxides, carbon monoxide and carbon dioxide. At the boiling point, ammonia, carbon dioxide and hydrogen
cyanide are liberated.
11. TOXICOLOGICAL
INFORMATION
TOXICITY
DATA: Rat:
Oral acute LD50=5570mg/kg; Inhalation >3900 ppm / 6h. Mouse: Oral LD50= 3150 mg/kg. Draize test, rabbit, eye: 100 mg
Severe. Skin rabbit: LD 50 =17 gm/
kg. Investigated as a tumorigen,
mutagen and reproductive effector.
Carcinogenicity:
Not listed by ACGIH, IARC, NIOSH, or OSHA.
Teratogenicity:
Embyro or fetus: Death, skin-rat=1200 mg / kg; stunted fetus growth. Oral-rat
TDLo = 2 g/kg; Specific Developmental Abnormalities: craniofacial and
musculoskeletal, oral-rat TDLo=7980 mg/kg.
Mutagenicity:
RTECS # LQ0525000 for mutation data.
12. ECOLOGICAL
INFORMATION
ECOTOXICITY:
When released into the soil, formamide may be biodegradable but it is
expected to leach into the ground water.
The chemical has an estimated bioconcentration factor (BCF) of less than
100. When released into the air, this material is expected to readily degrade
by reaction with photochemically produced hydroxyl radicals with a half-life of
less than 1 day. Minnow LC50=>500
mg/L/48 h.
13. DISPOSAL
CONSIDERATIONS
Observe
all federal, state and local regulations.
US EPA guidelines for the classification determination are listed in 40
CFR Parts 261.3.
14. TRANSPORT
INFORMATION
US ODOT
N/A
IMO Not
regulated as hazardous material.
IATA Not
regulated as hazardous material.
RID/ADR
Not regulated as hazardous material.
15. REGULATORY
INFORMATION
OSHA: Not
considered highly hazardous
TSCA: CAS#75-12-7
IS TSCA LISTED
SARA
CODES: CAS#75-12-7
ACUTE, CHRONIC
EINECS NO: 200 842 0
RISK
PHRASES: 36/37/38/47
SAFETY
PHRASES: 23/26/36/53
16.
OTHER INFORMATION Reviewed by BW, MJ
Revision
date 01/16/06
This information
is believed to be accurate and represents the information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no
liability resulting from its use. Users should make their own investigations to
determine the suitability of the information for their particular purposes.
Abbreviations:
N/A Not
Applicable
N.D.A. No data available
TLV-STEL Threshold Limit
Values (Short-Term Exposure Limit)
TLV-TWA Threshold Limit
Values (Time-Weighted Average)
OSHA PEL-TWA OSHA Permissible Exposure Level