MATERIAL SAFETY DATA SHEET


1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

Product: BCP Phase Separation Reagent
Cat. No:  BP 151

Molecular Research Center, Inc.
5645 Montgomery Rd.
Cincinnati, Ohio 45212
USA 1-888-841-0090

Product Name:  BCP Phase Separation Reagent
Chemical Formula: C3H6BrCl
Molecular Weight: 157.44
NFPA RATINGS: (scale 0-4)     Health=2       Fire=1      Reactivity=0      

HMIS RATINGS: (scale 0-4)     Health=2       Fire=1      Reactivity=0       PPE=H

CHEMTREC EMERGENCY NUMBER     1-800-424-9300


2. COMPOSITION / INFORMATION ON INGREDIENTS

Component                                      CAS No       Percent
1-Bromo-3-Chloropropane          109-70-6         100%
Synonyms: 3-Bromopropyl chloride, 1,3-CHBP, omega-chlorobromopropane, 1-chloro-3-bromopropane(DOT),  3-chloropropyl  bromide.


3. HAZARD IDENTIFICATION

ROUTES OF EXPOSURE:
Skin     Yes
Ingestion     Yes
Inhalation     Yes

ACUTE EFFECTS: Harmful if inhaled or swallowed.  Causes eye and skin irritation. Material is irritating to mucous membranes and upper respiratory tract and can result in dizziness and headache. Ingestion may cause gastrointestinal irritation with nausea, vomiting and diarrhea with potential liver and kidney damage.


4. FIRST AID

EYE CONTACT: Check for and remove any contact lenses. Flush eyes with water for 15 min, holding eyelids open.  Obtain medical attention.

SKIN CONTACT: Flush skin with soap and water for 15 min.; remove contaminated clothing and thoroughly wash before reuse.

INHALATION: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration.  Obtain medical attention.

INGESTION: If swallowed, wash mouth out if person is conscious. Do not induce vomiting unless directed so by medical personnel. Obtain medical attention.


5. FIRE FIGHTING MEASURES

EXTINGUISHING MEDIA: May be combustible at high temperatures. Extinguishing media appropriate tp surrounding fire conditions. Small fire: Use dry chemical powder. Large fire: Use water spray, fog or foam. Do not use water jet. Emits toxic fumes under fire conditions (chloride, bromide).

SPECIAL FIRE FIGHTING PROCEDURES: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.


6. ACCIDENTAL RELEASE MEASURES

PERSONAL PROTECTIVE EQUIPMENT FOR SPILL CONDITIONS: Note that accidental releases may be subject to special reporting requirements and other regulatory mandates. Check and comply with local laws and regulations.  Use gloves and other appropriate protective covering to avoid skin contact. Use goggles, face shield or other eye protection.  Contain spill with an inert absorbant such as vermiculite, sand or earth. Place spill material in a suitable container and hold for disposal. Avoid breathing vapor, mist or gas.


7. HANDLING AND STORAGE

Store in a cool, dry place in sealed containers. Practice good laboratory techniques when handling this substance. Wash hands thoroughly after handling. Use adequate ventilation. Avoid breathing vapor, mist or gas.


8. EXPOSURE CONTROLS / PERSONAL PROTECTION

For routine operations wear safety glasses, latex gloves and a chemical apron to avoid contact with eyes, skin and clothing. Facilities using this chemical should be equipped with an eyewash station and safety shower. Use adequate ventilation to keep airborne contrations below the permissible exposure limits. (No PELS are listed for this chemical).


9. PHYSICAL AND CHEMICAL PROPERTIES

Appearance: Clear, colorless liquid
Odor: Chloroform-like, sweetish odor
Vapor pressure: 6.6 mbar @20 °C
Density: 1.5920
Boiling point: 142 - 145 °C
Melting point: - 59 °C
Flash point: Closed cup 45 °C(113 °F)
Insoluble in water.


10. STABILITY AND REACTIVITY
Stable under normal temperatures and pressures.

INCOMPATIBILITIES: Heat, ignition sources, strong bases, strong oxidizing agents, magnesium, zinc, aluminum.
DECOMBUSTION PRODUCTS: Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide, hydrogen bromide gas.


11. TOXICOLOGICAL INFORMATION

RTECS# TX4113000
Rat:inhalation, LC50=5668 mg/m3; oral, LD50=930 mg/kg. Mouse:oral, LD50=1290 mg/kg.

CARCINOGENICITY: NOT LISTED BY ACGIH, NIOSH, NTP OR OSHA.


12. ECOLOGICAL INFORMATION

ECOTOXICITY: LC50 (24 hr) goldfish 75 mg/L; 24 HLC50(24 hr)goldfish:75 mg/L.


13. DISPOSAL CONSIDERATIONS

Keep in sealed containers until final disposal. Dispose of in a manner consistent with federal, state and local regulations. Not listed as banned from land disposal according to RCRA.


14. TRANSPORT INFORMATION

IATA, IMO, RID/ADR:
Shipping name: 1-bromo-3-chloropropane
Hazard Class: 6.1
UN Number: 2688
Packing Group: III


15. REGULATORY INFORMATION
European/ International Regulations: European Labeling in Accordance with EC Directives.
Hazard Symbols: XN
Risk Phrases: R20/22 Harmful by inhalation and if swallowed.
R36/37/38 Irritating to eyes, respiritory system and skin.
Safety Phrases: S26 In case of eye contact, rinse immediately with plenty of water and seek medical advice.
S37/39  Wear suitable gloves and eye/face protection.
WGK (Water Danger/Protection) CAS # 109-70-6:3.
United Kingdom Occupational Exposure Limits
Canada: CAS# is listed in Canada's DSL List and Ingredient Disclosure List.
Exposure Limits: CAS# 109-70-6: OEL-Russia: STEL 3 mg/m3
US Federal
   TSCA: CAS # 109-70-6 is listed on the TSCA 8(b) inventory.
   OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
16. OTHER INFORMATION    Reviewed by BW, MJ. Revised: 10/15/03

This information is believed to be accurate and represents the information currently available to us.  However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use.  Users should make their own investigations to determine the suitability of the information for their particular purposes.

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Last modified: January 22, 2004