MATERIAL SAFETY DATA SHEET

 

1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

 

Product:                 High Efficiency Hybridization System (with or without formamide).

Cat. No:                 HS 114, HS 114F

 

Molecular Research Center, Inc.

5645 Montgomery Rd.

Cincinnati, Ohio 45212

USA 1-800-841-0900

 

Product Name: High Efficiency Hybridization System

Chemical Formula: A formulation.

Molecular Weight: N/A

HMIS Rating (scale 0-4)   Health=2    Fire=1    Reactivity= 0     PPE=C

 

CHEMTREC EMERGENCY NUMBER:   1-800-262-8200

                                                                                                                                                                                                                                    

 

2. COMPOSITION / INFORMATION ON INGREDIENTS

 

Component                                             CAS No.                   Percent

High Efficiency Hyb Solution              N/A                           Proprietary Information

Formamide                                               75-12-7                     < 50 % (Note: Ingredient of HS-114F only)

                                                                                                                                                                                                                                     

 

3. HAZARD IDENTIFICATION

 

ROUTES OF EXPOSURE:            Skin                         Yes

                                                           Ingestion                 Yes

                                                           Inhalation                Yes

 

ACUTE EFFECTS: Causes eye and skin irritation.  Exposure may cause irritation to mucous membranes and upper respiratory tract.  Harmful if swallowed.

 

CHRONIC EFFECTS: Prolonged or repeated exposure to reagents containing formamide may cause adverse reproductive effects.  May cause fetal effects.  See FORMAzol MSDS for more detailed information relating to formamide.

                                                                                                                                                                                                                                       

 

4. FIRST AID

 

In case of contact, immediately flush eyes or skin with water for at least 15 min while removing contaminated clothing and shoes.  If inhaled, remove to fresh air.  If not breathing, give artificial respiration.  If breathing is difficult, give oxygen.  If swallowed, wash out mouth with water provided person is conscious.  If victim is conscious and alert, give 2-4 cupfuls of milk or water.  Seek medical attention.  Wash contaminated clothing before reuse.

                                                                                                                                                                                                                                     

 

5. FIRE FIGHTING MEASURES

 

Negligible fire hazard when exposed to heat or flame.  Extinguishing media: water spray, carbon dioxide, dry chemical powder or appropriate foam.  Special fire fighting procedures: may emit toxic fumes under fire conditions.  Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

                                                                                                                                                                                                                                     


 

6. ACCIDENTAL RELEASE MEASURES

 

Evacuate unnecessary personnel from area. Provide adequate general or local exhaust ventilation. If adequate ventilation is unavailable, wear self-contained breathing apparatus.  Wear appropriate protective eyeglasses or chemical safety goggles.  Wear appropriate protective gloves and protective clothing to prevent skin exposure.  Absorb on sand or vermiculite and place in containers for disposal.  Ventilate area and wash spill site after material pickup is complete.

                                                                                                                                                                                                                                     

 

7. HANDLING AND STORAGE

 

Irritant.  Keep container closed.  Store in a cool dry place.  Wear lab coat, gloves and eye protection and provide adequate ventilation.   Avoid contact with skin, eyes and clothing. Wash hands thoroughly after handling the reagent.

                                                                                                                                                                                                                                     

 

8. EXPOSURE CONTROLS/ PERSONAL PROTECTION

 

For routine operations wear lab coat, gloves and safety glasses to avoid contact with eyes, skin and clothing.  Ensure availability of eyewash and safety shower.  Avoid prolonged or repeated inhalation and skin exposure.

                                                                                                                                                                                                                                     

 

9. PHYSICAL AND CHEMICAL PROPERTIES

 

Appearance:          Clear, light orange liquid

Assay:                      >99 %

Solubility:                 Water, ethanol

                                                                                                                                                                                                                                     

 

10.  STABILITY AND REACTIVITY

 

STABILITY: Stable under normal temperatures and pressures.

 

INCOMPATIBILITIES: Strong oxidizing agents, bromine trifluoride, iodine heptafluoride and potassium chlorate.  In addition, HS-114F (with formamide) is incompatible with aluminum, acids, bases, calcium nitrate,  pyridine, iodine and  sulfur trioxide.

 

HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS: Toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides, ammonia and chlorine.

                                                                                                                                                                                                                                     

 

11. TOXICOLOGICAL INFORMATION

                 

May be harmful by inhalation, ingestion, or skin absorption.  Causes eye and skin irritation.  Material is irritating to mucous membranes and upper respiratory tract.  To the best of our knowledge, the chemical, physical, and toxicological properties of this formulation have not been thoroughly investigated.  HS-114F containing formamide may pose a potential birth defect hazard.

                                                                                                                                                                                                                                     

 

12. ECOLOGICAL INFORMATION      No data available.

                                                                                                                                                                                                                                     

 

13. DISPOSAL INFORMATION

 

Dissolve or mix with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.  Observe all federal, state and local environmental regulations.

                                                                                                                                                                                                                                     

 

14. TRANSPORT INFORMATION          No data available.

                                                                                                                                                                                                                                     

 

15. REGULATORY INFORMATION     No data available.

                                                                                                                                                                                                                                     

 

16. OTHER INFORMATION              Reviewed by          BW, MJ

                                                                  Revision date         01/16/06

 

This information is believed to be accurate and represents the information currently available to us.  However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use.  Users should make their own investigations to determine the suitability of the information for their particular purposes.

 

Abbreviations:

N/A                                            Not Applicable