1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Product: BCP Phase Separation Reagent
Cat. No: BP 151
Molecular Research Center, Inc.
5645 Montgomery Rd.
Cincinnati, Ohio 45212
USA 1-888-841-0090
Product Name: BCP Phase Separation Reagent
Chemical Formula: C3H6BrCl
Molecular Weight: 157.44
Synonyms: trimethylene bromochloride;
3-bromopropyl chloride; omega-chlorobromopropane; 1-chloro-3-bromopropane
(DOT); 3-chloropropyl bromide.
NFPA RATINGS: Health=2 Fire=2 Reactivity=0
HMIS RATINGS: (scale 0-4) Health=2 Fire=2 Reactivity=1 PPE=H
CHEMTREC EMERGENCY NUMBER: Only in the event of an emergency
involving a spill, leak, fire exposure or accident. USA: 1-800-424-9300; International: 1-703-527-3887
2. COMPOSITION / INFORMATION ON INGREDIENTS
Component CAS
No Percent
1-Bromo-3-Chloropropane 109-70-6 100%
EINECS
No.
203-697-1
3. HAZARD IDENTIFICATION
OSHA HAZARD:
Combustible liquid, harmful if ingested.
ROUTES OF EXPOSURE: Skin Yes
Ingestion Yes
Inhalation Yes
ACUTE
EFFECTS: Harmful if inhaled or swallowed. Chemical permeator causing eye and skin
irritation. Material is irritating to
mucous membranes and upper respiratory tract and can result in dizziness and
headache. Ingestion may cause
gastrointestinal irritation with nausea, vomiting and diarrhea with potential
liver and kidney damage.
4. FIRST AID
EYE
CONTACT: Check for and remove any
contact lenses. Flush eyes with water for 15 min., holding eyelids open. Obtain medical attention.
SKIN
CONTACT: Flush skin with soap and water for 15 min. Remove contaminated clothing and thoroughly wash before
reuse. Cover the irritated skin with an
emollient.
INHALATION: Remove from exposure to fresh air immediately. If not breathing, give artificial
respiration. Obtain medical attention.
INGESTION: If swallowed, wash mouth out if person is
conscious. Do not induce vomiting
unless directed so by medical personnel. Obtain medical attention. Loosen tight clothing such as a collar, tie
belt or waistband.
5. FIRE FIGHTING MEASURES
FLASH
POINTS: Closed cup 45C (113F)
FIRE
HAZARDS: Combustible in the
presence of an open flame and sparks.
EXTINGUISHING
MEDIA: May be combustible at
high temperatures. Extinguishing media
appropriate to surrounding fire conditions.
Small Fire: Use dry chemical powder. Large Fire: Use water spray, fog or
foam. Do not use water jet. Emits
toxic fumes under fire conditions (chloride, bromide).
SPECIAL
FIRE FIGHTING PROCEDURES: Wear
self-contained breathing apparatus and protective clothing to prevent contact
with skin and eyes.
6. ACCIDENTAL RELEASE MEASURES
PERSONAL
PROTECTIVE EQUIPMENT FOR SPILL CONDITIONS: Note that accidental releases may be subject to special reporting
requirements and other regulatory mandates.
Check and comply with local laws and regulations. Use gloves and other appropriate protective
covering to avoid skin contact. Ensure adequate ventilation. Use goggles, face shield or other eye
protection. Contain spill with an inert
adsorbent such as vermiculite, sand or earth.
Place spill material in a suitable container and hold for disposal. Wash spill site after pickup is complete.
Avoid breathing vapor, mist or gas.
7. HANDLING AND STORAGE
Store in a cool, dry place in sealed
containers. Ensure good ventilation at
the workplace. Practice good laboratory techniques when handling this
substance. After using the chemical,
wash hands thoroughly. Use adequate ventilation
and avoid breathing vapor, mist or gas.
Empty containers pose a fire risk and any residue should be evaporated
under a fume hood. Keep away from
incompatibles such as oxidizing agents, metals and alkalis.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
For routine operations wear safety glasses,
latex gloves and a chemical apron to avoid contact with eyes, skin and
clothing. Facilities utilizing this
chemical should be equipped with an eyewash station and safety shower. Use adequate ventilation to keep airborne
concentrations below the permissible exposure limits. (No PELS are listed for this chemical). Wash contaminated clothing before reuse. Wash thoroughly after handling.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Clear,
colorless liquid.
Odor: Chloroform-like,
sweetish odor.
Molecular Weight: 157.44
PH: N/A
Refractive Index: 1.486
Vapor Pressure: 6.6 mbar @ 20 C
Density: 1.5920
at 25 C ( 77 F)
Boiling point: 144 -145 C (291-295 F)
Melting point: - 59 C
Flash point: Closed
Cup 45 C (113 F)
Solubility in water: Insoluble
Specific gravity: 1.592 (water=1)
Solubility: Insoluble
in cold water, hot water.
Partition coefficient: log Kow: 2.2 n-octanol/water
10. STABILITY AND REACTIVITY
Stable under normal temperatures and
pressures.
INCOMPATIBILITIES: Heat, sparks, ignition sources, strong
bases, strong oxidizing agents, magnesium, zinc, aluminum.
DECOMBUSTION
PRODUCTS: Hydrogen chloride,
phosgene, carbon monoxide, carbon dioxide, and hydrogen bromide gas.
11. TOXICOLOGICAL INFORMATION
RTECS# TX4113000 DOT: POISON B, 6.1, III
Rat: Inhalation: LC50=5668 mg/m3;
oral LD50=930 mg/kg; Mouse: oral
LD50=1290 mg/kg. LCLo/2H: 7270 mg/m3.
CARCINOGENICITY: Not listed by ACGIH, NIOSH, NTP OR
OSHA.TARGET ORGAN DATA.
To the best of our knowledge the acute and
chronic toxicity of this substance is not fully known.
12. ECOLOGICAL INFORMATION
ECOTOXICITY: Harmful to fish; LC50 (24 hr) goldfish 75
mg/l- 24 h.
Possibly hazardous short-term degradation
products are not likely; however, long-term degradation products are possible.
The products of degradation are as toxic as
the product itself.
13. DISPOSAL CONSIDERATIONS
Keep in sealed containers until final
disposal. Dispose of in a manner
consistent with federal, state and local regulations. Contact a licensed
professional waste disposal service to dispose of this material.
14. TRANSPORT INFORMATION
DOT regulations:
Shipping
Name: 1-Bromo-3-Chloropropane
UN
Number: 2688
Hazard Class: 6.1 poisonous
material; Packing Group: III
Land Transportation ADR/RID:
Danger code (Kemler): 60
15. REGULATORY INFORMATION
European/International
Regulations
European Labeling in Accordance with EC
Directives
Hazard Symbols: XN Harmful
Risk Phrases:
R20/22 Harmful
by inhalation and if swallowed.
R36/37/38 Irritating to eyes, respiratory
system and skin.
R52/53 Harmful to aquatic organisms, may
cause long-term adverse effects in the aquatic environment.
Safety Phrases:
9
Keep container
in a well-ventilated place.
23 Do
not breath gas / fumes / vapor / spray.
26 In case of eye contact, rinse immediately with plenty of water and seek medical advice.
36
Wear suitable
protective clothing.
60 This
material and its container must be
disposed of as hazardous waste.
61
Avoid release to the
environment.
WGK (Water Danger/ Protection) CAS # 109-70-6: 3
United Kingdom Occupational Exposure Limits
Canada: CAS# 109-70-6 is listed in Canada’s
DSL List and Ingredient Disclosure List
Exposure Limits: CAS# 109-70-6: OEL-Russia:
STEL 3 mg/m3 US Federal
TSCA:
CAS # 109-70-6 is listed on the TSCA 8(b) inventory.
OSHA: Hazardous by definition of Hazard
Communication Standard (29 CFR 1910.1200).
16. OTHER INFORMATION
Reviewed
by BW, MJ
Creation
date 10/12/98
Revision date 2/01/09
This information is believed to be accurate
and represents the information currently available to us. However, we make no
warranty of merchantability or any other warranty, express or implied, with
respect to such information, and we assume no liability resulting from its use.
Users should make their own investigations to determine the suitability of the
information for their particular purposes.
Abbreviations:
N/A Not
Applicable
N.D.A. No data
available
TLV-STEL Threshold
Limit Values (Short-Term Exposure Limit)
TLV-TWA Threshold
Limit Values (Time-Weighted Average)
OSHA PEL-TWA OSHA
Permissible Exposure Level